Investigation of Distempervirus and Parvovirus Infections in Dogs
Keywords:
CDV, CPV, ELISAAbstract
CDV and CPV are significant viral agents that frequently cause fatal infections in both domestic and wild dogs. In this study, a total of 95 animals, including both healthy individuals and those exhibiting gastrointestinal and neurological symptoms, aged between 6 and 24 months, were serologically examined for CDV and CPV infections using the ELISA test. According to the manufacturer's instructions, the assay range for CDV was specified as 0.7 ng/ml to 200 ng/ml, with a sensitivity value of 0.665 ng/ml. Among the total 95 animals, 48 (50.52%) with good general health had antibody titers ranging between 7 and 20, while 9 (9.47%) had titers between 50 and 85. In animals showing lethargy, diarrhea, vomiting, and neurological symptoms, 22 (23.15%) had titers between 7 and 20, 10 (10.52%) between 20 and 35, 12 (12.63%) between 35 and 50, and 4 (4.2%) between 50 and 85. In terms of CPV antibodies, 88 (92.63%) were found to be positive. In conclusion, the study data indicate the necessity of developing and strictly implementing strategies to combat CDV and CPV infections. Further studies are required to investigate the genetic variability of these viruses, the effectiveness of vaccine-induced antibodies in protecting against local strains, and the pathogenesis of the diseases.
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